Poor Ovarian Reserve treatment in India
Seek proven treatment for poor ovarian reserve from one of the best IVF doctor in Mumbai
Poor ovarian reserve (POR) refers to a reduced count of ovarian follicular pool in women who belong to the reproductive age group. These days, poor ovarian reserve is one of the main causes of infertility in couples.
Generally, women more than 35 years of age have a poor ovarian reserve, but women below 35 years are detected with it. Poor ovarian reserve (POR) or premature ovarian aging can occur due to stress, lifestyle, and even environmental hazards.
Other reasons for poor ovarian reserve are
• Ovarian Endometriosis
• Genital Tuberculosis
• Thyroiditis – Autoimmune Disease
• Turners Mosaic Syndrome – Chromosomal Disorder
• Fragile X Syndrome – Genetic Disorders
Visit one of our IVF centre in India for diagnosing poor ovarian reserve and seeking appropriate treatment.
Diagnosis of poor ovarian reserve
Anti-mullerian Hormone AMH Test – This test measures the level of anti-müllerian hormone (AMH) in the blood. The anti-müllerian hormone (AMH) throws light on the patient’s chances of getting pregnant and detecting menstrual issues and the health of women suffering from ovarian cancer.
Ultrasound Antral Follicular Count – It is a transvaginal ultrasound test performed that measures the ovarian reserve. It is done during the initial phase of the menstrual cycle. The conducting doctor can view and the number of egg containing follicles developing on both the ovaries.
Other tests suggested include –
· X-Ray of the chest
· Sputum AFB,
· Mantoux test,
· Blood IgG & Ig M
· TB PCR of the endometrium to look for tuberculosis.
· Thyroid Profile, Thyroid Antibodies, and Karyotyping test to detect Turner’s syndrome.
· FMR1 DNA test to detect Fragile X syndrome
In Mumbai, we have one of the best IVF doctor in Mumbai who offers the latest poor ovarian reserve treatment. Most IVF specialists suggest egg freezing and oocyte retrieval for egg preservation to young unmarried women with poor ovarian reserve.
Poor Ovarian Reserve Treatment options aimed at improving the reserve include
• Adjuvants such as micronized DHEAS
• Pre-treatment with testosterone gel
• Coenzyme Q,
• Whey proteins
On completing these treatments, one of the most reliable IVF doctor in India suggests going ahead with ovarian stimulation and intrauterine insemination
– IUI to get pregnant and then proceed to with an IVF cycle in case of failure.
In ovarian stimulation, the IVF doctor suggests growth hormone in combination with heavy standard or mild ovarian stimulation. The gonadotropin recommended dose is 375-450 IU/day starting from day 2 along with 4-8 units of growth hormone .
IVF cycle on patients less than 35 years who have undergone poor ovarian reserve treatment are likely to have better outcomes as they have a better yield of eggs and embryos.
In the case of older patients with poor ovarian reserves, their IVF cycle is likely to have poor outcomes since they have extremely less eggs or no eggs during the egg retrieval process, along with the chances of poor fertilization. In such cases, good-quality embryos are collected and frozen across multiple cycles.
Once an adequate number of embryos are collected, they are thawed and transferred in the uterus through a blastocyst transfer of a sequential transfer leading to high chances of getting pregnant. There have been cases of patients with poor ovarian reserve getting pregnant through the treatment as mentioned above.
At our IVF centre in Mumbai, we also offer Ovarian Rejuvenation. This treatment involves superior techniques of ovarian tissue activation or Mitochondrial spindle transfer. Also, the IVF clinic can recommend five days of daily GCSF subcutaneously followed by intraovarian injection of bone marrow stem cells or platelet activated plasma either through laparoscopy or ultrasound. These procedures are still in the experimental stage, and their outcomes are not definite.
Our IVF centre is one of India’s leading IVF centers known for its commendable service and latest IVF and ART technology on par with international standards. It advises egg donation is the last and most feasible option for patients with poor ovarian reserve as it has a nearly 90% chance of a successful pregnancy.
Various causes that lead to poor ovarian reserve are genetic defects such as Turner’s syndrome or Fragile X syndrome – a gene defect or injuries, infection or surgery or radiation or chemotherapy that could have damaged the ovaries.
The ovarian reserve is an indicator of the patient’s ability to conceive and deliver a healthy baby. It is essential for patients who find it difficult to conceive or wish to delay their pregnancy to undergo this testing to plan for proper fertility treatments at their desired time.
If age is on the patient’s side, then the patient can improve the ovarian reserve by adopting a healthy lifestyle, including diet, the right amount of exercise along with relaxation and massage.
Yes, the levels of AMH fluctuate. They vary from person to person, from time to time, and from laboratory to another laboratory. Also, patients with polycystic ovary syndrome (PCOS) can have high levels of AMH.