Many couples suffer from infertility in Mumbai. It is due to the lifestyle they spend, or it could also be due to genetics. Couples approach fertility clinics in Mumbai, asking for a treatment option.
If you are suffering from a similar problem and seeking treatment, then IMSI could be a good option for you.
Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) is an advanced assisted reproductive technology. So, if you suffer from severe male factor infertility, the IMSI procedure can be beneficial.
IMSI is an advanced form of ICSI having a magnification power 16 times more compared to ICSI.
IMSI can provide you with various advantages like improved embryo quality and selection of viable sperms. It also helps to minimize the chances of abortion.
In ICSI, the specialist observes your sperms under a microscope of 500 times magnification. However, in IMSI, your sperm is being examined under high power of 6600 times before microinjection.
IMSI allows your specialist to see the detailed structure of your sperms. It helps in detecting potential abnormalities in the head, middle, and tail of the sperm. After that, your specialist picks out the healthiest sperms.
IMSI treatment is performed in the following order:
Once your specialist collects the semen sample, they will treat it with a specific solution to remove any impurities. After that, the specialist will separate the viable cells using centrifugation on the day of your procedure.
Your specialist examines the sperms under a microscope. It helps them choose the most suitable sperm for injecting into the egg. Usually, sperms with abnormal head size and large vacuoles are not selected. So, this way, the most viable sperms are chosen.
Your specialist uses a needle transvaginally under ultrasound-guidance to collect the eggs. After the egg collection, your specialist first washes the egg with an enzyme to get rid of the unwanted components. Later on, using a microscope, the best eggs are selected.
Your doctor will place the selected sperm in a pipette and inject it into the egg. The microinjected eggs are kept in a sterile culture petri dish in an incubator overnight.
The specialist will keep checking the eggs at regular intervals to observe the signs of fertilization. Once the embryo forms, it is inserted into the mother’s uterus.
You can go for a pregnancy test after 2 weeks to confirm pregnancy and take further steps.
You are suitable for IMSI treatment if you have:
Even though IMSI has its advantages, like any other treatment, it has its disadvantages as well. These include:
So, your IVF specialist will only recommend this treatment when it is necessary because of the disadvantages.
Through IMSI, couples have achieved higher pregnancy and live birth rates. Furthermore, it has reduced miscarriage rates significantly. IMSI also improves the success rate of IVF treatment as it increases the rate of embryo implantation.
IMSI assists males with a poor prognosis. It is more helpful than ICSI if you have previous IVF or ICSI failures. IMSI has improved egg fertilization rates, quality embryos, and higher pregnancy rates.